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Thyroid doesn't produce. An empty stomach, one-half to one hour before breakfast. Synthroid is a brand name for levothyroxine sodium. Synthroid may rapidly swell and disintegrate resulting in choking, gagging, the tablet getting stuck in your throat, or difficulty swallowing. Synthroid is the most commonly prescribed of all the thyroid supplements. Aside from the treatment of hormone deficiency, Synthroid can also be used to treat the enlargement of the thyroid glands.